Diseases
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They make you sick.
Auregh-Rosen Syndrome
Kayla and Meekie have this. Virulent but not often deadly.[1] Also Margeaux Davis from "A Distant Sun", if I remember right.
Cancer
Amaranth and Persey have various cancers. Cancer has become "more pernicious in humans since they've become spacefarers, and no one's sure why."[1]
Cerrmoniah
Kuriel has this. A disease that consumes the nerve endings as fast as they're rebuilt.[1]